Dr. Hanspeter Schöb
phone: +41 (0)44 63 48250
fax: +41 (0)44 63 48204 Research InterestsKeywords Education Previous Positions and Research Experience List of Publications |  |
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My main research interest lies in developmental biology. After obtaining a PhD in plant epigenetics at the university of Basel, I am now a Postdoc in Ueli Grossniklaus’ group at the Institute of Plant Biology. My research focuses i) on the identification of genes required for megasporogenesis in Arabidopsis thaliana, and ii) on the elucidation of RNA based regulatory mechanisms controlling plant reproductive development.
epigenetics, RNA silencing, gametophytes, plant reproduction
| 1996 - 2001 | Graduate studies in Genetics Friedrich Miescher Institute, Basel, Switzerland ('magna cum laude') PhD thesis under the supervision of Prof. Dr. Frederick Meins: "Sense and antisense gene silencing in Tobacco are mechanistically related" |
| 1995 - 1996 | Friedrich Miescher Institute, Basel, Switzerland, Switzerland Diploma thesis under the supervision of Prof. Dr. F Meins: "Silencing of glucanohydrolases in Nicotiana sylvestris" |
| 1991 - 1996 | Undergraduate studies (Diplom) in Biology II (Molecular Biology) Biozentrum of the University of Basel, Switzerland |
| 2002 - pres | Postdoctoral researcher in Prof. Dr. Ueli Grossniklaus laboratory Institute of Plant Biology, University of Zurich, Switzerland |
| 2001 - 2002 | Postdoctoral researcher in Prof. Dr. Frederick Meinsthe laboratory Friedrich Miescher Institute, Basel, Switzerland |
Schöb H, Grossniklaus U. (2006) The first high-resolution DNA "methylome". Cell. 126(6):1025-8.
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In co-first authorship: Di Serio F, Schöb H, Iglesias A, Tarina C, Bouldoires E, Meins F Jr (2001) Sense- and antisense-mediated gene silencing in tobacco is inhibited by the same viral suppressors and is associated with accumulation of small RNAs. Proc. Natl. Acad. Sci. USA 98(11):6506-6510.
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Crété P, Leuenberger S, Iglesias VA, Suarez V, Schöb H, Holtorf H, van Eeden S, Meins F Jr (2001) Graft transmission of induced and spontaneous post-transcriptional silencing of chitinase genes. Plant J. 28(5):493-501.
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Kunz C, Schöb H, Leubner-Metzger G, Glazov E, Meins F Jr. (2001) Beta-1,3-Glucanase and chitinase transgenes in hybrids show distinctive and independent patterns of posttranscriptional gene silencing. Planta 212:243-249.
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Holtorf H, Schöb H, Kunz C, Waldvogel R, Meins F Jr (1998) Stochastic and nonstochastic post-transcriptional silencing of chitinase and Beta-1,3-glucanase genes involves increased RNA turnover - Possible role for ribosome-independent RNA degradation. The Plant Cell 11:471-483.
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Schöb H, Kunz C, Meins F Jr (1997) Silencing of transgenes introduced into leaves by agroinfiltration: a simple, rapid method for investigating sequence requirements for gene silencing. Mol. Gen. Genet. 256:581-585.
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Kunz C, Schöb H, Stam M, Kooter J, Meins F Jr (1996) Developmentally regulated silencing and reactivation of tobacco chitinase transgene expression. Plant J. 10:437-450.