Dr. Yanru Li
phone: +41 (0)44 63 48253
fax: +41 (0)44 63 48204 Research InterestsKeywords Education Previous Positions and Research Experience |  |
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I focus basically on the dynamic chromatin organization during the sporogenesis and gametogenesis stage. Linker histones (H1) has been proved to. be important for the nucleosome structure and the chromatin organization, H1 linker histones are important for the nucleosome structure and the chromatin organization. RNAi-based downregulation of the H1 complement induces severe developmental aberration and sterility, H1 variants also greatly influence the DNA methylation landscape. According to former colleagues' work, during the sporogenesis, the onset of spore mother cell (SMC) differentiation is marked by a reduction in heterochromatin associated with changes of some epigenetic markers and a transient eviction of H1 both on the female and male lineage. My main aim is to study if H1 eviction facilitates epigenetic reprogramming underlying the establishment of novel transcriptional programs?
Epigenetic, linker histone, citrunillation, plant, sporogenesis
| 2016 - 2019 | Master in Genetics and Physiology Clermont Auvergne University, France |
| 2014 - 2016 | Bachelor in Biology: Cell Biology and Physiology Clermont Auvergne University, France |
| 2019 | Master2 internship, GReD laboratory, Clermont Auvergne University, (Period: 6 months) Supervisor: WALTZER Lucas. Mission: Role of the epigenetic regulator TET in the development of Drosophila hematopoietic system. |
| 2018 | Voluntary internship at the GReD Laboratory, Clermont Auvergne University, (Period: 4 months) Supervisor: TATOUT Christophe. Mission: Molecular and phenotypic analysis of mutated plants for the kaku4 gene in Arabidopsis thaliana. |
| 2017 | Internship Master1, Laboratory Genome and Plant Development, Perpignan (Period: 2 months) Supervisor: PONTVIANNE Frederic. Mission: Role of the nucleolus in the organization of chromatin in Arabidopsis thaliana. |
| 2014 | Attached to the Pasteur Institute of Shanghai, China (Period: 2 months) Supervisor: Changbin CHEN. Mission: Interaction between Candida albicans and its host. |